high throughput molecular docking against actl8 (TargetMol)
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high throughput molecular docking against actl8
High Throughput Molecular Docking Against Actl8, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/high+throughput+molecular+docking+against+actl8/ACTL8+Protein%2C+Human%2C+Recombinant/pm41621692-198-0-12
Average 94 stars, based on 1 article reviews
High Throughput Molecular Docking Against Actl8, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/high+throughput+molecular+docking+against+actl8/ACTL8+Protein%2C+Human%2C+Recombinant/pm41621692-198-0-12
Average 94 stars, based on 1 article reviews
high throughput molecular docking against actl8 - by Bioz Stars,
2026-09
94/100 stars
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Drug discovery:Article Title: Momordin Ic suppresses breast cancer growth by targeting ACTL8‑dependent glutamine metabolism and PI3K/AKT/mTOR-MYC. Article Snippet: Glutamine metabolism is a key driver of tumor progression, yet the molecular basis and prognostic relevance of glutamine metabolism–related genes in breast cancer (BC) remain incompletely defined.. In this study, integrated analysis of public datasets identified Actin-like protein 8 (ACTL8) as a key prognostic gene significantly upregulated in BC tissue and associated with poor patient survival.. In vitro, shRNA knockdown of ACTL8 reduced MYC expression and its downstream targets SLC1A5 and GLS1, suppressing cell proliferation, migration and invasion. |